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Via Sam Ruby, a post from Jerry Cuomo who asks (rhetorically) :

It is worth standardizing an agile platform for our generation’s dynamic web applications?

Doesn't sound unreasonable. He has in mind a particular stack of tools: Ajax, REST, Atom, scripting languages. But for data in general, all he offers is SQL. As Sam points out, SQL is a weak link.

Predictably, I'd suggest RDF (with direct REST & SPARQL for queries) instead. Considerably more agile and Web-oriented - doesn't need up-front schemas, is a data model designed for the Web, an evolution of the link. Going further, I'd suggest delegating potential commodity parts like a store with RESTful inferfaces to a different kind of Platform.

See also: A Relational View of the Semantic Web, Semantic Web Client Library, ActiveRDF.